Chilled platelet study

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August undefined, 2024

WebPlatelet transfusion refractoriness due to anti-HLA antibodies. Conscious objection or unwillingness to receive blood products. Planned post-operative extracorporeal … WebSep 26, 2024 · PRESS RELEASE. THOR Network investigators have been awarded over 26 million dollars by the US Department of Defense for a research program that will examine the efficacy and safety of cold …

CHIlled Platelet Study Clinical Research Trial Listing ( Acute Blood ...

WebCHIlled Platelet Study (CHIPS) STATUS Recruiting; End date Mar 31, 2024; participants needed 1000; sponsor Philip Spinella; Save Print Send. Updated on 21 October 2024 ... WebCHIPS (CHIlled Platelet Study) is a phase 3, multicenter, international, randomized, partial-blinded, adaptive, non-inferiority, storage duration ranging trial in adult and … great scholarships kenya

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WebThe CHIlled Platelet Study trial will compare the efficacy and safety of standard room temperature-stored platelets with platelets that are cold-stored (1°C-6°C), that is, … WebCHIlled Platelet Study (CHIPS) STATUS Recruiting; End date Mar 31, 2024; participants needed 1000; sponsor Philip Spinella; Save Print Send. Updated on 21 October 2024 ... A phase 3 randomized partial blind storage duration ranging study in patients undergoing complex cardiac surgery that will compare the transfusion of cold stored platelets to ... WebMay 7, 2024 · Chilled Platelets Platelet administration plays an integral role in balanced transfusion and, in people, may improve survival from trauma ( 11, 13, 62 ). Both retrospective and prospective data suggest that lower platelet count on admission is associated with increased risk of death among human trauma patients ( 63, 64 ). great school bedford hills elementary school

CHIlled Platelet Study "CHIPS" - Full Text View

CHIlled Platelet Study Clinical Research Trial Listing ( Acute …

WebOfficial Title CHIlled Platelet Study Summary A phase 3 randomized partial blind storage duration ranging study in patients undergoing complex cardiac surgery that will compare the transfusion of cold stored platelets to standard room temperature stored platelets. WebThe CHIlled Platelet Study trial will compare the efficacy and safety of standard room temperature-stored platelets with platelets that are cold-stored (1°C-6°C), that is, chilled, with a maximum of storage up to 21 days in adult and pediatric patients undergoing complex cardiac surgical procedures. floral cheyne alvechurchWebMar 31, 2024 · Overview. A phase 3 randomized partial blind storage duration ranging study in patients undergoing complex cardiac surgery that will compare the transfusion of cold stored platelets to standard room temperature stored platelets. The primary objective is to establish that cold stored platelets have a non-inferiority (or superiority) to room ... great school backpacks

"WebApr 8, 2024 · No Study Results Posted on ClinicalTrials.gov for this Study. Krachey E, Viele K, Spinella PC, Steiner ME, Zantek ND, Lewis RJ. The design of an adaptive clinical trial to evaluate the efficacy of platelets stored at low temperature in surgical patients. J Trauma Acute Care Surg. 2024 Jun;84 (6S Suppl 1):S41-S46. doi: 10.1097/TA.0000000000001876. " - Chilled platelet study

Chilled platelet study

Design and logistical considerations for the randomized adaptive …

WebPlatelet count increased after platelet transfusion for all study arms (P < 0.05). Multiple electrode aggregation response to all agonists increased after platelet transfusion for all … WebCHIlled Platelet Study. Summary. A phase 3 randomized partial blind storage duration ranging study in patients undergoing complex cardiac surgery that will compare the …

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WebJul 12, 2024 · In a state where traumatic injury is common, Medical Center caregivers treat many patients suffering from profound blood loss. These patients must have platelets – … WebCHIlled Platelet Study (CHIPS) Brigid Flynn. ExtraCorporeal Membrane Oxygenation for 2024 novel Coronavirus Acute Respiratory Disease (ECMOCARD) Brigid Flynn. Opioid Disposal Survey Aaron LacKamp. Pain – Clinical. Dorsal spInal cord STImulatioN vs mediCal management for the Treatment of low back pain (DISTINCT)

WebDec 21, 2024 · The CHIlled Platelet Study trial has been funded and will be implemented in approximately 20 clinical centers. Early randomization to enable procurement of cold-stored platelets with different storage durations will be required, as well as a platelet tracking system to eliminate platelet wastage and maximize trial efficiency and economy. ... WebChilled Platelet Study. Status: Recruiting. Description: The purpose of this research study is to compare the transfusion of cold-stored (refrigerated) platelets to standard room …

WebApr 8, 2024 · Acute respiratory distress syndrome, need for and duration of renal support, renal failure, septic shock. Measures of end organ injury [ Time Frame: within 48 hours of first study platelet transfusion ] If BUN, creatinine, lactate, troponin, alanine … WebJun 14, 2024 · This study is to identify the mechanism of platelet clearance after cold storage and develop a method for platelet cold storage. Approach and Results: ... cold storage of platelets is that chilled platelets are cleared rapidly from circulation after transfusion 2-4, 11. Cold storage induces platelets to change in morphology from discoid to

WebCold-stored platelets are experiencing a resurgence as a treatment for hypovolemic shock—a shift in transfusion practice that could impact lab technologists cross-trained to …

WebResearch Grants Chilled Platelet Study (ChiPS), U.S. Department of Defense Subspecialties cardiovascular and thoracic anesthesiology, perioperative echocardiography Contact UPMC Presbyterian 200 Lothrop Street, Suite C-200 Pittsburgh, PA 15213 [email protected] (412) 647-3260 great scholarship turkeyWebJul 3, 2024 · Electron microscopy has been a valuable tool for the study of platelet biology and thrombosis for more than 70 years. Early studies using conventional transmission and scanning electron microscopy (EM) provided a foundation for our initial understanding of platelet structure and how it changes upon platelet activation. floral chicken clipartWebCHIlled Platelet Study "CHIPS" (CHIPS) Official Title: CHIlled Platelet Study : Secondary IDs: Study Status. Record Verification: April 2024 ... within 24 hours prior to receiving … floral cherry plumWebDec 9, 2024 · Clinical trials have shown improved bleeding cessation with cold platelets. 11 Studies from our group have shown that you can transfer platelets into the cold after 3 or 4 days without an obvious impact on the … floral cheri blum printsWebDec 21, 2024 · The CHIlled Platelet Study trial has been funded and will be implemented in approximately 20 clinical centers. Early randomization to enable procurement of cold-stored platelets with different ... great school bird watchWebMajor Goals:The major goals of this study are to develop, evaluate, and refine neonatal and postoperative feeding protocols for the pediatric cardiac intensive care unit with the hope of increasing enteral nutrition and minimizing feeding … great school boundary mapWebFeb 17, 2024 · Recent data have shown that cold platelets stored for up to 21 days may improve clotting function compared with room-temperature platelets stored for up to 5 to … floral chicken