WebAppropriate lysogens of these strains with corynephage beta, carrying known class II tox premature polypeptide chain termination mutations [C7sup-1(betatox-30) and C7sup-2(betatox-45)], each produce a 62,000-dalton polypeptide with nicotinamide adenine dinucleotide: elongation factor-2 adenosine diphosphate ribosyltransferase activity in … WebDec 4, 2024 · Corynebacterium diphtheriae is the main etiological agent of diphtheria, a global disease causing life-threatening infections, particularly in infants and children. Vaccination with diphtheria toxoid protects against …
Bacteriophage Qβ - an overview ScienceDirect Topics
WebMar 21, 1994 · Corynephage beta: Mutation(s): 0 EC: 2.4.2.36: UniProt: Find proteins for P00588 (Corynephage beta) Explore P00588 . Go to UniProtKB: P00588. Entity Groups Sequence Clusters: 30% Identity 50% Identity 70% Identity 90% Identity 95% Identity 100% Identity: UniProt Group: P00588: Protein Feature View Expand: Reference Sequence; WebMay 19, 2016 · In 1951 Freeman reported the paradigm-shifting discovery that a nontoxinogenic isolate of C. diphtheriae acquired the ability to produce DT after contact with a specific corynephage called B (Freeman 1951), and in 1952, Freeman and Morse proposed a possible relationship between lysogeny and toxinogenicity in C. diphtheriae … front elevation design of house ground floor
Corynebacterium ulcerans and Corynebacterium …
Webdetermined by tBLASTn query of the assembled genomes using select references: Corynephage beta A and B subunits (NCBI accession no. P00588), Corynephage omega beta Diphtheria toxin (NCBI accession no. P00587), and Corynephage beta Diphtheria toxin homolog (NCBI accession no. P00589). Publicly available . C. diphtheriae WebFeb 7, 1994 · Background. The CRM197 protein is a nontoxic form of diphtheria toxin but is immunologically indistinguishable from the diphtheria toxin. CRM197 is produced by C. diphtheriae infected by the nontoxigenic phage beta 197 created by nitrosoguanidine mutagenesis of the toxigenic corynephage beta (Uchida, T. et al. 1971, Nature New … Diphtheria toxin is an exotoxin secreted by mainly by Corynebacterium diphtheriae but also by Corynebacterium ulcerans and Corynebacterium pseudotuberculosis. the pathogenic bacterium that causes diphtheria. The toxin gene is encoded by a prophage called corynephage β. The toxin causes the disease in humans by gaining entry into the cell cytoplasm and inhibiting protein ghost flights of illegals