WebMar 29, 2024 · Title: Colony‑stimulating factor CSF2 mediates the phenotypic plasticity of small‑cell lung cancer by regulating the p‑STAT3/MYC pathway. Single Nucleotide … Webhelp help. Description. Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, …
Frontiers Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases ...
WebFeb 21, 2024 · Il2 and Csf2 gene expression, mediated by NFkappaB, are increased as T cells undergo activation and aging. Interferon-gamma and granulocyte/monocyte colony … WebDec 22, 2024 · The identified CSF2 pathway could provide novel insights into the pathergic response of BD-like disease and offer new opportunities for personalized treatment. Disclosures. The authors declare no competing interests. Open Research. Data Availability Statement. Data are available upon request. Citing Literature. grand european travel weston hotel
Molecular Mechanisms of the Anti-Inflammatory Effects of ...
WebJun 23, 2024 · CSF2 plays an important role in directing M1 polarization after blockade of the CSF1/CSR1R signaling pathway, which is involved in M2 polarization. Shelby et al. showed a positive correlation between PD-L1 and CSF2 concentrations in gingival crevicular fluid of patients diagnosed with periodontitis ( 42 ). WebJun 4, 2024 · Granulocyte-macrophage colony-stimulating factor (GM-CSF, or CSF2) was first described in the conditioned media of mouse lung tissue following LPS injection, ... There are four main signaling pathways triggered by CSF2R . After binding of GM-CSF to its receptor, Janus-kinase-2 (JAK-2) is recruited to the cytoplasmic domain of the β … WebFeb 1, 2024 · The role of the CSF2/CENPE pathway in kidney cells treated with PM and lactoferrin was crucial. In a mouse model, lactoferrin ameliorated PM-indused kidney abnormalities by regulating necroptosis, fibrosis, autophagy and the CSF2/CENPE pathway. Lactoferrin may be a novel therapeutic or preventive agent for renal disorders … chinese bumper stickers