Webcytoplasm. In true hairy cells, only the cytoplasm displays any of the fine, “hair-like” projections commonly associated with these cells. Fraying around the nucleus suggests artifactual aberrations that formed during preparation of the blood smear. Likewise, hairy cells do not have the cytoplasmic clearing, WebApr 1, 2012 · Clear cell change and fine cytoplasmic granulations are typically seen in association with the hemosiderin deposition and/or necrosis. The cytoplasmic clearing may reflect phagocytic activity of the renal carcinoma cells in these settings. Clear cell change can become quite extensive in some tumors causing morphologic confusion with …
Integrative bioinformatics links HNF1B with clear cell ... - PubMed
WebBernard-Soulier syndrome (BSS) is an autosomal-recessive bleeding disorder caused by biallelic variants in the GP1BA, GP1BB, and GP9 genes encoding the subunits GPIbα, GPIbβ, and GPIX of the GPIb-IX complex. Pathogenic variants usually affect the extracellular or transmembrane domains of the receptor subunits. We investigated a … WebA clear cell's plasma membrane is highly folded, more so on the apical and lateral surfaces. The cytoplasm of clear cells contains large amounts of glycogen and many mitochondria. Melanocytes appear as clear cells when in the stratum basale of the skin, and Langerhans' cells appear as clear cells in the stratum spinosum. [1] philip aspden organist
Renal Cell Carcinoma With Clear Cell and Papillary Features
WebMay 16, 2008 · Large, clear cytoplasmic vacuoles were defined when at least half of the cytoplasm demonstrated a clear vacuole with sharp borders. Furthermore, nuclear … WebThe cytoplasmic clearing is due to glycogen, although some cells may also contain mucin. 276 In some tumors, the cytoplasm may be focally oxyphilic, and in a rare variant it is completely oxyphilic. Benign and borderline clear cell tumors are rare. WebCytoplasmic clearing was also observed. The mitotic figures were easily found (×400). The tumor cells were strongly and diffusely positive for (E) S100 and (F) SOX10 (×100), (G) moderately positive for Syn, and (H) negative for HMB45. FIGURE 3. Figure 3. Molecular characteristics of the lesion. philip asiodu