Lamp1 tumor
TīmeklisScore. LAMP1. Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis; CD molecules (417 aa) Predicted Functional Partners: GTPBP1. GTP-binding protein 1; Promotes degradation of target mRNA species. Tīmeklis2015. gada 23. janv. · In terms of malignant tumors, LAMP1 has been identified expressing higher in many cancers, especially in metastatic cancer cells, playing an important role in tumor invasion and metastasis, but ...
Lamp1 tumor
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Tīmeklis2024. gada 10. apr. · Autophagy, an important cellular stress response mechanism, is often exploited by a variety of cancer cells to sustain rapid growth under stresses such as nutrient deprivation and hypoxia. Autophagy also plays a key role in tumor resistance to chemotherapy, radiotherapy or targeted therapy. Inhibition of autophagy is … TīmeklisThe two glycoproteins were detected in the cytosol of tumor cells with varying intensity, LAMP-1 showing again enhanced expression. In conclusion, novel data on LAMP-1 …
TīmeklisThe LMS arrays included tumors from different locations, clinical stage, and grade. NEU1 expression was low or undetectable in most cases, and LAMP1 expression … Tīmekliswe demonstrate that LAMP1 is a direct target in UBL4A-induced tumor suppression and inhibition of autophagy. HPbetaCD and HPgammaCD facilitate cholesterol …
TīmeklisProduct Details Antibody Details Format Details Citations & References Brand: BD Pharmingen™ Alternative Name: LAMP-1; LGP-120; LGP-A; P2B Reactivity: Mouse (QC Testing) Isotype: Rat SD, also known as Sprague-Dawley (outbred) IgG2a, κ Immunogen: Plasma membrane fraction of mouse embryo NIH 3T3 cell line TīmeklisConclusion: These results show that LAMP-1 and LAMP-2 are activation markers for normal mast cells. The lack of LAMP translocation after activation of leukemic mast …
Tīmeklis2015. gada 23. janv. · Expression of lysosome-associated membrane protein-1 (LAMP1) on the cell surface is one such modification where a lysosomal protein LAMP1 gets …
TīmeklisAlso implicated in tumor cell metastasis (By similarity). By similarity. 2 publications. GO annotations. Aspect Term; Cellular Component: alveolar lamellar body Source:MGI. ... However, mice deficient in both LAMP1 and LAMP2 are embryonic lethal, with the accumulation of autophagic vacuoles in many tissues (PubMed:15121881). toy alligator plasticTīmeklisIts 5-year survival rate remains very low. Lysosomal associated membrane proteins (LAMPs), including LAMP1 and LAMP2, are major protein components of the lysosome, which also plays an important role in tumor evolution. Our previous studies have confirmed that LAMP1 and LAMP2 play an important role in the evolution and … toy alphardTīmeklis2024. gada 16. aug. · Abstract. Lysosome associated membrane protein‑1 (LAMP1) is a heavily glycosylated lysosomal membrane protein, which is able to protect the … toy amazon corporation