Phospho-sting-s365
WebJul 7, 2024 · Phospho-S365 acts as a docking site for IRF3, a transcription factor that is phosphorylated and activated by TBK1, leading to transcriptional induction of type I … WebAnti-Phospho-STING-S365 antibody produced in rabbit. View Price and Availability. Sigma-Aldrich. ABF124. Anti-cGAS Antibody. from rabbit, purified by affinity chromatography. View Price and Availability. Sigma-Aldrich. D7290. Deoxyribonucleic acid from herring sperm. single-stranded for hybridization.
Phospho-sting-s365
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WebSTING is a four transmembrane (a.a. 21-41, 47-67, 87-106, 116-136) protein with both its N- and C-terminal ends exposed intracellularly (a.a. 1-20 and 137-379).The C-terminal cytoplasmic tail contains the c-di-GMP-binding domain (CBD; a.a. 153-340) with two c-di-GMP-binding regions (a.a. 162-167 & 238-241). Spécificité WebJul 7, 2024 · To initiate signaling, serine 365 (S365) in the C-terminal tail (CTT) of STING is phosphorylated, leading to induction of type I interferons (IFNs). Additionally, evolutionary conserved...
Web靶标信息. STING is a 379 amino acid containing signaling protein that acts as an important component of innate immune signaling. This signaling protein is able to activate both NF … WebJan 29, 2015 · Phosphorylated (p-S365) or nonphosphorylated peptides (S365) were calculated by selectively using ions specific for each species (also see table S1 and …
WebJun 3, 2024 · In clones in which VPS13C protein expression had been successfully restored, phospho-STING and phospho-TBK1 were restored to WT ... cat# 19781, … WebPhospho-STING-Ser366 polyclonal antibody (Stimulator of interferon genes protein) binds to endogenous Stimulator of interferon genes protein only when phosphorylated at Ser366. Phosphorylation by TBK1 leads to activation and production of IFN-beta. Following cyclic nucleotide (c-di-GMP or cGAMP)-binding, activation and translocation from the ...
WebStimulator of interferon genes (STING, TMEM173, MITA) is a transmembrane adaptor protein that is a critical component of the cellular innate immune response to pathogenic cytoplasmic DNA (1,2). STING is a …
Webphospho irf 3 ser396 (Cell Signaling Technology Inc) Cell Signaling Technology Inc is a verified supplier Cell Signaling Technology Inc manufactures this product About News Press Release Team Advisors Partners Contact Bioz Stars Bioz vStars 96 Buy from Supplier Structured Review Cell Signaling Technology Incphospho irf 3 ser396 css textarea width 100 percentWebPhospho-B-Raf (Ser445) Antibody detects endogenous levels of B-Raf when phosphorylated at serine 445. Species Reactivity: Human, Mouse, Rat, Monkey Species predicted to react based on 100% sequence homology: css text arialWebWestern blot analysis of extracts of THP-1 cells, using Phospho-STING-S365 antibody (AP1199) at 1:1000 dilution.THP-1 cells were treated by PMA (80 nM) at 37℃ for … early african church fathers blackWebJan 13, 2024 · This novel vector, STINGPOX, produces cyclic di-AMP, a STING agonist, which drives IFN signaling critical to the anti-tumor immune response. We demonstrate that STINGPOX can drive IFN signaling in primary human cancer tissue explants. css textarea resize vertical onlycss textarea vertical align textWebJun 25, 2024 · In infected cells, STING is phosphorylated on S366 (S365 in mouse) and is K63 linked ubiquitinated, confirming the presence of its activated form at later time points following RNA virus infection, similarly to what has been observed by others after infection with DNA virus ( Chiang and Gack, 2024 ). Results early afternoon time crosswordWebPhospho-STING (Ser366) Antibody recognizes endogenous levels of STING protein only when phosphorylated at Ser366. Species Reactivity: Human Source / Purification Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser366 of human STING protein. css textarea样式