WebJun 24, 2024 · Michel R. Le May. TTM2 enrolled 1,900 adults with coma after OHCA of presumed cardiac or unknown cause, randomizing them to hypothermia at 33°C followed … WebJan 14, 2024 · Primary endpoint occurred in 5.6% of those with low-risk, 55.4% in the intermediate risk, and 92.3% in the high-risk groups; With a MIRACLE 2 score >2 (low-risk), the sensitivity was 97.9%. The specificity increased to 90.8% when the score was > 5 (high-risk); When compared to other predictive scoring tools at their end-point range, the …
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WebJul 30, 2024 · See page 4518 for the editorial comment on this article (doi: 10.1093/eurheartj/ehaa673) Introduction. Out-of-hospital cardiac arrest (OOHCA) occurs in over a quarter of a million patients a year globally and presents a major public health challenge. 1 There is an increasing recognition of a primary cardiac aetiology in OOHCA … WebPurpose: Targeted temperature management (TTM) may improve survival and functional outcome in comatose survivors of out-of-hospital cardiac arrest (OHCA), though the … birthday packages for boys
Implementation of Targeted Temperature Management After …
WebOct 12, 2024 · Dr. Kathryn Pendleton. The TTM2 trial (Dankiewicz J, et al. N Engl J Med. 2024;384:2283-94) is the most recent trial to address the question of TTM post-cardiac arrest. The TTM2 trial was an international, randomized controlled superiority trial of TTM at 33˚C vs normothermia (≤37.8˚C) for patients with coma following OHCA with any initial ... WebJul 30, 2015 · The study by Cronberg et al. in this June’s JAMA Neurology [3] attempts to shed light on the obscure area of neurological recovery post OOHCA. They report data from the original Targeted Temperature Management (TTM) trial [2], a multicentre, international, parallel group, randomised clinical trial comparing two strict target temperature ... WebDec 2, 2024 · The annual incidence of out‐of‐hospital cardiac arrest (OHCA) in the United States is nearly 400 000, with large regional variation in survival to hospital discharge … birthday packages for kids